| Tlr9 |
81897 |
Knockout |
Delayed wound healing |
| Tnf |
21926 |
Knockout |
Promotion of granulation tissue formation and delayed re-epithelialization |
| Tnfrsf1a |
21937 |
Knockout |
Accelerated wound healing; enhanced angiogenesis and collagen content; accelerated re-epithelialization with increased gene expression of TGF-beta1, CTGF, VEGF, Flt-1, and Flk-1 |
| Tnfsf14 |
50930 |
Knockout |
Impaired wound healing with characteristics of nonchronic and chronic ulcers |
| Tnxb |
81877 |
Knockout |
Reduced breaking strength of unwounded skin; after wounding, scars do not progress beyond the mechanical strength of uninjured skin; no obvious differences in the rate of wound closure |
| Tpm3 |
236479 |
Deletion of exon |
Accelerated wound healing; increased cell migration |
| Trp53 |
22059 |
Mutation |
Delayed wound closure |
| Trpc6 |
22068 |
Knockout |
Impaired wound healing |
| Tsc1 |
64930 |
Knockout |
Accelerated wound healing |
| Tsk2 |
109631 |
Knockout |
Delayed wound healing |
| Vangl2 |
93840 |
Knockout; Double Knockout |
Defective wound repair |
| Vav1 |
22324 |
Knockout |
Delayed wound healing |
| Vav3 |
57257 |
Knockout |
Delayed wound healing |
| Vegfa |
22339 |
Overexpression; inhibitor administration |
Promotion of lymphangiogenesis; systemic blockade of VEGFR-2 prevented lymphatic vessel formation |
| Vegfa |
22339 |
Overexpression |
Rapid wound closure |
| Vegfa |
22339 |
Protein administration |
Improved wound healing by locally up-regulating growth factors important for tissue repair and by systemically mobilizing bone marrow-derived cells |
| Vim |
22352 |
Knockout |
Delayed wound contraction, migration of fibroblasts into the wound site, and appearance of myofibroblasts at the wound site |
| Vtn |
22370 |
Knockout |
Delayed wound healing; extensive areas of delayed hemorrhage near the sprouting tips of microvessels between days 7 and 14 |
| Wfdc1 |
67866 |
Knockout |
Accelerated wound closure; elevated deposition of osteopontin and macrophage recruitment |
