Tlr9 |
81897 |
Knockout |
Delayed wound healing |
Tnf |
21926 |
Knockout |
Promotion of granulation tissue formation and delayed re-epithelialization |
Tnfrsf1a |
21937 |
Knockout |
Accelerated wound healing; enhanced angiogenesis and collagen content; accelerated re-epithelialization with increased gene expression of TGF-beta1, CTGF, VEGF, Flt-1, and Flk-1 |
Tnfsf14 |
50930 |
Knockout |
Impaired wound healing with characteristics of nonchronic and chronic ulcers |
Tnxb |
81877 |
Knockout |
Reduced breaking strength of unwounded skin; after wounding, scars do not progress beyond the mechanical strength of uninjured skin; no obvious differences in the rate of wound closure |
Tpm3 |
236479 |
Deletion of exon |
Accelerated wound healing; increased cell migration |
Trp53 |
22059 |
Mutation |
Delayed wound closure |
Trpc6 |
22068 |
Knockout |
Impaired wound healing |
Tsc1 |
64930 |
Knockout |
Accelerated wound healing |
Tsk2 |
109631 |
Knockout |
Delayed wound healing |
Vangl2 |
93840 |
Knockout; Double Knockout |
Defective wound repair |
Vav1 |
22324 |
Knockout |
Delayed wound healing |
Vav3 |
57257 |
Knockout |
Delayed wound healing |
Vegfa |
22339 |
Overexpression; inhibitor administration |
Promotion of lymphangiogenesis; systemic blockade of VEGFR-2 prevented lymphatic vessel formation |
Vegfa |
22339 |
Overexpression |
Rapid wound closure |
Vegfa |
22339 |
Protein administration |
Improved wound healing by locally up-regulating growth factors important for tissue repair and by systemically mobilizing bone marrow-derived cells |
Vim |
22352 |
Knockout |
Delayed wound contraction, migration of fibroblasts into the wound site, and appearance of myofibroblasts at the wound site |
Vtn |
22370 |
Knockout |
Delayed wound healing; extensive areas of delayed hemorrhage near the sprouting tips of microvessels between days 7 and 14 |
Wfdc1 |
67866 |
Knockout |
Accelerated wound closure; elevated deposition of osteopontin and macrophage recruitment |