Knockout of Adamts5 in Mus musculus

Gene symbol Adamts5
Gene name Similar To A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2); A Disintegrin-Like And Metallopeptidase (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2)
Gene entrez ID 632263
Gene aliases ADMP-2, ADAMTS11
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol ADAMTS5
HUGO gene ID 221
Gene entrez ID 11096
Genecards ADAMTS5

Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Impaired contraction and dermal collagen deposition
References Velasco et al. 2011

Contact: Vadim E. Fraifeld, MD, PhD
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