Knockout of C3 in Mus musculus

Gene symbol C3
Gene name Complement Component 3; Similar To Complement Component C3 Prepropeptide, Last
Gene entrez ID 12266
Gene aliases CPAMD1, ARMD9, C3a, C3b
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol C3
HUGO gene ID 1318
Gene entrez ID 718
Genecards C3

Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated early stages of wound healing; reduction in inflammatory infiltrate; increased accumulation of mast cells and advanced angiogenesis
References Rafail et al. 2015

Contact: Vadim E. Fraifeld, MD, PhD
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