Knockout of Ccl2 in Mus musculus

Gene symbol Ccl2
Gene name Chemokine (C-C Motif) Ligand 2
Gene entrez ID 20296
Gene aliases MCP1, MCP-1, MCAF, SMC-CF, GDCF-2, HC11, MGC9434
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol CCL2
HUGO gene ID 10618
Gene entrez ID 6347
Genecards CCL2

Intervention Knockout
Genetic background C57BL/6 (7% SJL)
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound re-epithelialization and angiogenesis; collagen synthesis was impeded with wounds containing significantly less hydroxyproline; no change in the number of wound macrophages
References Low et al. 2001

Contact: Vadim E. Fraifeld, MD, PhD
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