Knockout of Cxcr3 in Mus musculus

Gene symbol Cxcr3
Gene name Chemokine (C-X-C Motif) Receptor 3
Gene entrez ID 12766
Gene aliases CKR-L2, CMKAR3, IP10-R, MigR, CD183
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol CXCR3
HUGO gene ID 4540
Gene entrez ID 2833
Genecards CXCR3

Intervention Knockout
Genetic background FVB/N
Wound model Full-Thickness Excisional Punch
Wound Dimensions 20 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Thick keratinized scar with a thickening of both the epidermis and dermis; the dermis was disorganized with thick and long collagen fibrils and contained excessive collagen content; Pesented lower tensile/burst strength
References Yates et al. 2009
Yates et al. 2010

Contact: Vadim E. Fraifeld, MD, PhD
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