Knockout; overexpression of Egr1 in Mus musculus

Gene symbol Egr1
Gene name Early Growth Response 1
Gene entrez ID 13653
Gene aliases TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol EGR1
HUGO gene ID 3238
Gene entrez ID 1958
Genecards EGR1

Intervention Knockout; overexpression
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 30 mm
Wound Location Dorsum
Effect on skin wound healing Knockout: Impaired wound healing; overexpression: exuberant tissue repair, with enhanced collagen accumulation and increased tensile strength of incisional wounds
References Bryant et al. 2000
Wu et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
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