Knockout of Fga in Mus musculus

Gene symbol Fga
Gene name Fibrinogen Alpha Chain
Gene entrez ID 14161
Gene aliases 0
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol FGA
HUGO gene ID 3661
Gene entrez ID 2243
Genecards FGA

Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 15 mm
Wound Location Dorsum
Effect on skin wound healing Altered pattern of epithelial cell migration and increased epithelial hyperplasia; granulation tissue failed to adequately close the wound gap, resulting in persistent open wounds or partially covered sinus tracts; reduced tensile strength
References Drew et al. 2001
Grose and Werner 2004

Contact: Vadim E. Fraifeld, MD, PhD
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