Knockout of Il1rn in Mus musculus

Gene symbol Il1rn
Gene name Interleukin 1 Receptor Antagonist
Gene entrez ID 16181
Gene aliases IL1RA, ICIL-1RA, IL1F3, IRAP, IL-1RN, MGC10430
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)

Gene symbol IL1RN
HUGO gene ID 6000
Gene entrez ID 3557
Genecards IL1RN

Intervention Knockout
Genetic background BALB/c
Wound model Full-Thickness Excisional Punch
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Attenuated collagen deposition and delayed neovascularization; exaggerated neutrophil recruitment with augmented expression of IL-1s, TNF-alpha, and CXC chemokines (MIP-2 and KC)
References Ishida et al. 2006

Contact: Vadim E. Fraifeld, MD, PhD
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