Browse Sus scrofa domesticus genes (12)


Gene symbol Entrez ID Intervention Effect on wound healing
APCS 396921 local depletion by ionized agarose gel Accelerated wound healing
CALR 100381266 Protein administration Accelerated wound healing; increase in epithelial migration and granulation tissue formation; marked proliferation of basal keratinocytes and dermal fibroblasts; dense cellularity of the dermis with notably increased numbers of macrophages and well-organized collagen fibril deposition
EGF 397083 Protein administration Accelerated re-epithelialization
EGF 397083 Protein administration Accelerated wound closure; improved wound healing quality in terms of number of arranged microvasculature, fibroblast migration and proliferation, collagen deposition and evolution of the inflammatory response
EGF 397083 Overexpression (Adenoviral transfection) Promotion of resurfacing; enhanced wound maturity
ERBB3 100126862 Overexpression (Adenoviral transfection) Promotion of resurfacing; enhanced wound maturity
FGF2 397643 Protein administration Better reconstruction quality in terms of hardness and the function of the stratum corneum
GJA1 397259 Peptide administration Decreased scar progenitor tissue area; promoted restoration of dermal histoarchitecture and mechanical strength; reduction in inflammatory neutrophil infiltration
HSP90AA1 397028 Peptide administration Accelerated wound healing; accelerated re-epithelialization
LTF 397649 Protein administration Accelerated re-epithelialization; increased keratinocyte proliferation and migration
NRG3 100158106 Overexpression (Adenoviral transfection) Promotion of resurfacing; enhanced wound maturity
VTN 397192 Protein administration Accelerated re-epithelialization; improved morphological features such as wound contraction, scar profile, and hair follicle density

Contact: Vadim E. Fraifeld, MD, PhD
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