Knockout of Fga in Mus musculus


Gene symbol Fga
Gene name Fibrinogen Alpha Chain
Gene entrez ID 14161
Gene aliases 0
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol FGA
HUGO gene ID 3661
Gene entrez ID 2243
Genecards FGA


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 15 mm
Wound Location Dorsum
Effect on skin wound healing Altered pattern of epithelial cell migration and increased epithelial hyperplasia; granulation tissue failed to adequately close the wound gap, resulting in persistent open wounds or partially covered sinus tracts; reduced tensile strength
References Drew et al. 2001
Grose and Werner 2004

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.