Knockout of Foxo1 in Mus musculus


Gene symbol Foxo1
Gene name Forkhead Box O1
Gene entrez ID 56458
Gene aliases FKH1
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol FOXO1
HUGO gene ID 3819
Gene entrez ID 2308
Genecards FOXO1


Intervention Knockout
Genetic background N/A
Wound model Full-Thickness Excisional Punch; Full-Thickness Incision
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated wound healing with enhanced keratinocyte migration; reduced granulation tissue formation; decreased collagen density; attenuated inflammatory response (only in heterozygous knockout)
References Mori et al. 2014
Xu et al. 2015

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.