| Intervention | Knockout |
| Genetic background | C57BL/6N |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 5 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Delayed wound healing; reduced granulation tissue formation; reduction in wound breaking strength; smaller scar area |
| References | Wankell et al. 2001 Grose and Werner 2004 Antsiferova et al. 2009 |