| Intervention | Knockout; antagonist administration |
| Genetic background | C57BL/6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 8 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Suppressed wound healing and angiogenesis; delayed wound healing after antagonist administration |
| References | Yahata et al. 2006 Kurosaka et al. 2009 |