Knockout of Il1rn in Mus musculus


Gene symbol Il1rn
Gene name Interleukin 1 Receptor Antagonist
Gene entrez ID 16181
Gene aliases IL1RA, ICIL-1RA, IL1F3, IRAP, IL-1RN, MGC10430
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol IL1RN
HUGO gene ID 6000
Gene entrez ID 3557
Genecards IL1RN


Intervention Knockout
Genetic background BALB/c
Wound model Full-Thickness Excisional Punch
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Attenuated collagen deposition and delayed neovascularization; exaggerated neutrophil recruitment with augmented expression of IL-1s, TNF-alpha, and CXC chemokines (MIP-2 and KC)
References Ishida et al. 2006

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.