Knockout; overexpression of Il5 in Mus musculus


Gene symbol Il5
Gene name Interleukin 5
Gene entrez ID 16191
Gene aliases IL-5, EDF, TRF
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol IL5
HUGO gene ID 6016
Gene entrez ID 3567
Genecards IL5


Intervention Knockout; overexpression
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 10 mm
Wound Location Dorsum
Effect on skin wound healing IL-5 overexpression vs. knockout: delayed wound healing with impaired re-epithelialization; delay in collagen deposition; increase in inflammatory cell infiltration; altered inflammatory response
References Leitch et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.