Knockout of Il6 in Mus musculus


Gene symbol Il6
Gene name Interleukin 6
Gene entrez ID 16193
Gene aliases IL-6, BSF2, HGF, HSF
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol IL6
HUGO gene ID 6018
Gene entrez ID 3569
Genecards IL6


Intervention Knockout
Genetic background C57BL/6J
Wound model Full-Thickness Excisional Punch
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound healing; minimal epithelial bridge formation; decreased inflammation, and granulation tissue formation
References Gallucci et al. 2000
Gallucci et al. 2004
Gallucci et al. 2006

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.