Knockout of Itga11 in Mus musculus


Gene symbol Itga11
Gene name Integrin Alpha 11
Gene entrez ID 319480
Gene aliases HsT18964
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol ITGA11
HUGO gene ID 6136
Gene entrez ID 22801
Genecards ITGA11


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions 25 mm
Wound Location Dorsum
Effect on skin wound healing Reduced granulation tissue formation and impaired wound contraction; dermal fibroblasts are unable to efficiently convert to myofibroblasts, resulting in scar tissue with compromised tensile strength
References Schulz et al. 2015

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.