Knockout of Alox5 in Mus musculus


Gene symbol Alox5
Gene name Arachidonate 5-Lipoxygenase
Gene entrez ID 11689
Gene aliases 5-LOX
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol ALOX5
HUGO gene ID 435
Gene entrez ID 240
Genecards ALOX5


Intervention Knockout
Genetic background SV129
Wound model Full-Thickness Excisional Punch
Wound Dimensions 10 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated wound healing with an upregulation of heme oxygenase-1 (HO-1)
References Brogliato et al. 2014

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.