| Intervention | Knockout |
| Genetic background | C57BL/6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 5 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Delay in wound closure; impaired wound contraction, granulation tissue formation, collagen synthesis, and reepithelialization |
| References | Hori et al. 2012 |