siRNA knockdown of Map3k1 in Mus musculus


Gene symbol Map3k1
Gene name Mitogen-Activated Protein Kinase Kinase Kinase 1
Gene entrez ID 26401
Gene aliases MEKK, MAPKKK1
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol MAP3K1
HUGO gene ID 6848
Gene entrez ID 4214
Genecards MAP3K1


Intervention siRNA knockdown
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 5 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound closure; impaired activation of Jun NH2-terminal kinases, induction of plasminogen activator inhibitor (PAI)-1, and restoration of cell-cell junctions of the wounded epidermis
References Deng et al. 2006

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.