Overexpression; antagonist andministration of Mir21a in Mus musculus


Gene symbol Mir21a
Gene name Microrna 21
Gene entrez ID 387140
Gene aliases hsa-mir-21, MIR-21
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol MIR21
HUGO gene ID 31586
Gene entrez ID 406991
Genecards MIR21


Intervention Overexpression; antagonist andministration
Genetic background C57BL
Wound model Full-Thickness Excisional Punch
Wound Dimensions 10 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Overexpression of miR-21: stronger wound contraction; antagomiR administration: delay of wound closure with impaired collagen deposition
References Wang et al. 2012

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.