| Intervention | Knockout |
| Genetic background | C57/BL6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 2.25 cm^2 |
| Wound Location | Dorsum |
| Effect on skin wound healing | Abnormal pattern and amount of collagen-rich granulation bed tissue; skin wound fibroblasts proliferated past the normal wound maturation phase |
| References | Atit et al. 1999 |