Knockout of Nfic in Mus musculus


Gene symbol Nfic
Gene name Nuclear Factor I/C
Gene entrez ID 18029
Gene aliases CTF, NF-I, CTF5
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol NFIC
HUGO gene ID 7786
Gene entrez ID 4782
Genecards NFIC


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 25 mm^2
Wound Location Dorsum
Effect on skin wound healing Accelerated wound closure; faster inflammatory stage; increased expression of PDGFA and PDGF-receptor alpha; reduced differentiation of fibroblasts to myofibroblasts
References Plasari et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.