| Intervention | Knockout |
| Genetic background | C57BL/6 or BALB/c |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 6 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Delayed wound closure with reduced neovascularization |
| References | Ekstrand et al. 2003 |