Overexpression of Nr3c1 in Mus musculus


Gene symbol Nr3c1
Gene name Nuclear Receptor Subfamily 3, Group C, Member 1
Gene entrez ID 14815
Gene aliases GR
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol NR3C1
HUGO gene ID 7978
Gene entrez ID 2908
Genecards NR3C1


Intervention Overexpression
Genetic background C57BL/6/DBA
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound healing; delayed re-epithelialization and formation of granulation tissue; reduced recruitment of granulocytes and macrophages; TGF-β1 and Kgf expression was repressed whereas TGF-β3 was up-regulated
References Sanchis et al. 2012

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.