| Intervention | Knockout |
| Genetic background | C57BL/6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 15 mm â |
| Wound Location | N/A |
| Effect on skin wound healing | Impaired angiogenesis, plasma extravasation and collateral growth |
| References | Carmeliet et al. 2001 |