Knockout of Ppp1r15a in Mus musculus


Gene symbol Ppp1r15a
Gene name Protein Phosphatase 1, Regulatory (Inhibitor) Subunit 15A; Myeloid Differentiation Primary Response Gene 116
Gene entrez ID 17872
Gene aliases GADD34
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol PPP1R15A
HUGO gene ID 14375
Gene entrez ID 23645
Genecards PPP1R15A


Intervention Knockout
Genetic background C57BL/6J
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated wound healing; reduced amounts of myosin IIA in migrating macrophages and myofibroblasts
References Tanaka et al. 2010

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.