Knockout of Ar in Mus musculus


Gene symbol Ar
Gene name Androgen Receptor
Gene entrez ID 11835
Gene aliases AIS, NR3C4, SMAX1, HUMARA
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol AR
HUGO gene ID 644
Gene entrez ID 367
Genecards AR


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated wound healing; enhanced inflammatory response through a localized increase in TNF-alpha expression; no acceleration in keratinocyte- and fibroblast-specific knockouts
References Lai et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.