| Intervention | Knockout |
| Genetic background | C57BL/6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 8 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Delayed wound closure and re-epithelization; inhibited angiogenesis; reduction in immunoreactive vascular endothelial growth factor (VEGF) in granulation tissues |
| References | Kamoshita et al. 2006 |