Knockout of Sfpi1 in Mus musculus


Gene symbol Sfpi1
Gene name Sffv Proviral Integration 1
Gene entrez ID 20375
Gene aliases PU.1, SPI-A, OF, SFPI1, SPI-1
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SPI1
HUGO gene ID 11241
Gene entrez ID 6688
Genecards SPI1


Intervention Knockout
Genetic background N/A
Wound model Full-Thickness Excisional Punch; Full-Thickness Incision
Wound Dimensions 0.5 cm^2
Wound Location Dorsum
Effect on skin wound healing Accelerated wound healing with reduced fibrosis; incapacity to raise the standard inflammatory response, due to a lack of macrophages and functioning neutrophils
References Martin et al. 2003
Cooper et al. 2005


Contact: Vadim E. Fraifeld, MD, PhD
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