Knockout of Smad3 in Mus musculus


Gene symbol Smad3
Gene name Mad Homolog 3 (Drosophila)
Gene entrez ID 17127
Gene aliases JV15-2, HsT17436
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SMAD3
HUGO gene ID 6769
Gene entrez ID 4088
Genecards SMAD3


Intervention Knockout
Genetic background C57B6/Black, Swiss/SVEV129 or SVEV129
Wound model Full-Thickness Excisional Punch; Ear Hole
Wound Dimensions 4 mm ⌀
Wound Location Dorsum; Ear
Effect on skin wound healing Accelerated dorsal wound healing; ear wounds are enlarged resulting from changes in extracellular matrix molecules
References Ashcroft et al. 1999
Arany et al. 2006

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.