Knockout of Smad4 in Mus musculus


Gene symbol Smad4
Gene name Similar To Mad Homolog 4 (Drosophila); Mad Homolog 4 (Drosophila)
Gene entrez ID 17128
Gene aliases DPC4
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SMAD4
HUGO gene ID 6770
Gene entrez ID 4089
Genecards SMAD4


Intervention Knockout
Genetic background N/A
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound closure and remodeling; increased angiogenesis and inflammation
References Owens et al. 2010
Yang et al. 2012

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.