Overexpression of Smad7 in Mus musculus


Gene symbol Smad7
Gene name Mad Homolog 7 (Drosophila)
Gene entrez ID 17131
Gene aliases 0
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SMAD7
HUGO gene ID 6773
Gene entrez ID 4092
Genecards SMAD7


Intervention Overexpression
Genetic background N/A
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated re-epithelialization; increase in keratinocyte proliferation; reduced Smad2 activation; increased activation of extracellular signal-regulated kinase (Erk)
References Han et al. 2011

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.