Knockout of Snai2 in Mus musculus


Gene symbol Snai2
Gene name Snail Homolog 2 (Drosophila)
Gene entrez ID 20583
Gene aliases SLUGH1, SNAIL2
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SNAI2
HUGO gene ID 11094
Gene entrez ID 6591
Genecards SNAI2


Intervention Knockout
Genetic background 129
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3.5 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Reduced re-epithelialization; increased expression of the Slug target genes keratin 8 and E-cadherin at wound margins; 40% of mice developed non-healing cutaneous ulcers in response to chronic UVR
References Savagner et al. 2005
Hudson et al. 2009

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.