Overexpression of Socs3 in Mus musculus


Gene symbol Socs3
Gene name Suppressor Of Cytokine Signaling 3
Gene entrez ID 12702
Gene aliases SSI-3, CIS3, SOCS-3, Cish3
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SOCS3
HUGO gene ID 19391
Gene entrez ID 9021
Genecards SOCS3


Intervention Overexpression
Genetic background N/A
Wound model Full-Thickness Excisional Punch
Wound Dimensions 5 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Impaired wound healing; atrophied wound-margin epithelia and augmented response of keratinocytes; a prolonged persistence of neutrophils and macrophages; elevated levels of TGF-beta1
References Linke et al. 2010

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.