knockout of Spi1 in Mus musculus


Gene symbol Spi1
Gene name Sffv Proviral Integration 1
Gene entrez ID 20375
Gene aliases PU.1, SPI-A, OF, SFPI1, SPI-1
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SPI1
HUGO gene ID 11241
Gene entrez ID 6688
Genecards SPI1


Intervention knockout
Genetic background N/A
Wound model Full-Thickness Excisional Punch; Full-Thickness Incision
Wound Dimensions N/A ⌀
Wound Location forepaw
Effect on skin wound healing Scar-free repair; altered growth factor and cytokine profile; cell death is reduced, and dying cells are instead engulfed by stand-in phagocytic fibroblasts
References Martin et al. 2003

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.