Knockout of Spp1 in Mus musculus


Gene symbol Spp1
Gene name Secreted Phosphoprotein 1
Gene entrez ID 20750
Gene aliases BSPI, ETA-1
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol SPP1
HUGO gene ID 11255
Gene entrez ID 6696
Genecards SPP1


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Incision
Wound Dimensions N/A
Wound Location Dorsum
Effect on skin wound healing Decreased level of debridement; greater disorganization of matrix; alteration of collagen fibrillogenesis leading to small diameter collagen fibrils; tensile properties of the wounds were unchanged
References Liaw et al. 1998

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.