Knockout of Tgfb1 in Mus musculus


Gene symbol Tgfb1
Gene name Transforming Growth Factor, Beta 1
Gene entrez ID 21803
Gene aliases CED, TGFbeta
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol TGFB1
HUGO gene ID 11766
Gene entrez ID 7040
Genecards TGFB1


Intervention Knockout
Genetic background N/A
Wound model Full-Thickness Excisional Punch
Wound Dimensions 0.25 cm^2
Wound Location Dorsum
Effect on skin wound healing Decreased granulation tissue formation, vascularity, collagen deposition, epithelialization and a marked inflammatory infiltrate
References Shah et al. 1999
Crowe et al. 2000
Yang et al. 2001
Brown et al. 1995

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.