Knockout of Tgfbr2 in Mus musculus


Gene symbol Tgfbr2
Gene name Transforming Growth Factor, Beta Receptor Ii
Gene entrez ID 21813
Gene aliases 0
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol TGFBR2
HUGO gene ID 11773
Gene entrez ID 7048
Genecards TGFBR2


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 4 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated wound closure and re-epithelization; reduced collagen deposition and remodeling; reduced extent of wound contraction, and elevated macrophage infiltration
References Martinez-Ferrer et al. 2010

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.