Knockout of Tlr4 in Mus musculus


Gene symbol Tlr4
Gene name Toll-Like Receptor 4
Gene entrez ID 21898
Gene aliases hToll, CD284, TLR-4, ARMD10
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol TLR4
HUGO gene ID 11850
Gene entrez ID 7099
Genecards TLR4


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound healing; decreased numbers of infiltrating macrophages in the dermis and decreased TGF-β and CCL5 mRNA expression
References Suga et al. 2014

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.