| Intervention | Knockout |
| Genetic background | 129:C57b1/6 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 4 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Delayed wound healing; reduced re-epithelialization, collagen synthesis, and angiogenesis; impaired recruitment of neutrophils and macrophages |
| References | Mori et al. 2004 Shen et al. 2008 |