Knockout of C3 in Mus musculus


Gene symbol C3
Gene name Complement Component 3; Similar To Complement Component C3 Prepropeptide, Last
Gene entrez ID 12266
Gene aliases CPAMD1, ARMD9, C3a, C3b
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol C3
HUGO gene ID 1318
Gene entrez ID 718
Genecards C3


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Accelerated early stages of wound healing; reduction in inflammatory infiltrate; increased accumulation of mast cells and advanced angiogenesis
References Rafail et al. 2015

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.