| Intervention | Protein administration |
| Genetic background | N/A |
| Wound model | Retrospective cohort study |
| Wound Dimensions | N/A |
| Wound Location | N/A |
| Effect on skin wound healing | rhPDGF was more effective than standard therapy in both helping a wound to heal and preventing amputation; the effect was similar to the efficacy estimated from previously published randomized controlled trials |
| References | Margolis et al. 2005 |