| Intervention | Knockout; overexpression |
| Genetic background | FVB/N for OE, C57BL/6 for KO |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 5 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Both knockout and overexpression led to a markedly delayed wound healing |
| References | Giangreco et al. 2009 |