Knockout of Ccl2 in Mus musculus


Gene symbol Ccl2
Gene name Chemokine (C-C Motif) Ligand 2
Gene entrez ID 20296
Gene aliases MCP1, MCP-1, MCAF, SMC-CF, GDCF-2, HC11, MGC9434
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol CCL2
HUGO gene ID 10618
Gene entrez ID 6347
Genecards CCL2


Intervention Knockout
Genetic background C57BL/6 (7% SJL)
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Delayed wound re-epithelialization and angiogenesis; collagen synthesis was impeded with wounds containing significantly less hydroxyproline; no change in the number of wound macrophages
References Low et al. 2001

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.