Intervention | Knockout; overexpression |
Genetic background | 129:C57BL/6, C57BL/6:B6/SJL |
Wound model | Full-Thickness Excisional Punch |
Wound Dimensions | 6 mm â |
Wound Location | Dorsum |
Effect on skin wound healing | Knockout: delayed wound healing and inhibition in infiltration of neutrophils, macrophages, and cytokine expression; Overexpression: enhanced wound healing and cytokine expression |
References | Iwata et al. 2009 |