Knockout of Adamts5 in Mus musculus


Gene symbol Adamts5
Gene name Similar To A Disintegrin-Like And Metalloprotease (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2); A Disintegrin-Like And Metallopeptidase (Reprolysin Type) With Thrombospondin Type 1 Motif, 5 (Aggrecanase-2)
Gene entrez ID 632263
Gene aliases ADMP-2, ADAMTS11
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol ADAMTS5
HUGO gene ID 221
Gene entrez ID 11096
Genecards ADAMTS5


Intervention Knockout
Genetic background C57BL/6
Wound model Full-Thickness Excisional Punch
Wound Dimensions 3 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Impaired contraction and dermal collagen deposition
References Velasco et al. 2011

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.