| Intervention | siRNA knockdown |
| Genetic background | CD1 |
| Wound model | Full-Thickness Excisional Punch |
| Wound Dimensions | 3.5 mm â |
| Wound Location | Dorsum |
| Effect on skin wound healing | Impaired wound healing; inhibition of both re-epithelialization and granulation tissue formation; decrease of arteriole number |
| References | Melchionna et al. 2012 |