Knockout of Col7a1 in Mus musculus


Gene symbol Col7a1
Gene name Collagen, Type Vii, Alpha 1
Gene entrez ID 12836
Gene aliases 0
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol COL7A1
HUGO gene ID 2214
Gene entrez ID 1294
Genecards COL7A1


Intervention Knockout
Genetic background B6.Cg-Tg5Amc/J
Wound model Full-Thickness Excisional Punch
Wound Dimensions 6 mm ⌀
Wound Location Dorsum
Effect on skin wound healing Defects in dermal fibroblast migration and cytokine production in the granulation tissue; perturbation of laminin-332 organization during wound healing; strictly polarized expression of integrin α6β4 in basal keratinocytes
References Nyström et al. 2013

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.