Knockout of Cxcl11 in Mus musculus


Gene symbol Cxcl11
Gene name Similar To Small Inducible Cytokine B11 Precursor (Cxcl11) (Interferon-Inducible T-Cell Alpha Chemoattractant) (I-Tac); Chemokine (C-X-C Motif) Ligand 11
Gene entrez ID 56066
Gene aliases H174, b-R1, I-TAC, IP-9
Organism House mouse, Mus musculus (@AnAge)
Interactions Protein-protein interaction partners (@BioGRID)


Gene symbol CXCL11
HUGO gene ID 10638
Gene entrez ID 6373
Genecards CXCL11


Intervention Knockout
Genetic background FVB/N
Wound model Partial-Thickness Excisional Punch; Incision
Wound Dimensions 20 mm
Wound Location Dorsum
Effect on skin wound healing Delayed re-epithelialization; hypercellular and immature dermis noted even after 60 days; provisional matrix components persisted in the dermis, and the mature basement membrane components laminin V and collagen IV were severely diminished
References Yates et al. 2008

Contact: Vadim E. Fraifeld, MD, PhD
Head: Lab for the Biology of Aging, The Shraga Segal Department of Microbiology, Immunology and Genetics, Faculty of Health Sciences, Ben-Gurion University of the Negev
P.O. Box 653, Beer-Sheva 8410501, Israel
Email:
How to cite us:
If you would like to cite this database please use:
Yanai H, Budovsky A, Tacutu R, Barzilay T, Abramovich A, Ziesche R, Fraifeld VE. Tissue repair genes: the TiRe database and its implication for skin wound healing. Oncotarget. 2016; 7:21145-55.